MRC2 antibody (AA 120-300)

Catalog No. ABIN7146098

Product Details anti-MRC2 Antibody

Target: MRC2 (Mannose Receptor, C Type 2 (MRC2))

Binding Specificity: AA 120-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRC2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human C-type mannose receptor 2 protein (120-300AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MRC2

Target: MRC2 (Mannose Receptor, C Type 2 (MRC2))

Alternative Name: MRC2 (MRC2 Products)

Synonyms: MRC2 antibody, cd280 antibody, uparap antibody, clec13e antibody, endo180 antibody, Endo180 antibody, CD280 antibody, CLEC13E antibody, ENDO180 antibody, UPARAP antibody, mKIAA0709 antibody, uPARAP antibody, mannose receptor C type 2 antibody, mannose receptor, C type 2 antibody, MRC2 antibody, mrc2 antibody, Mrc2 antibody

Background:

Background: May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).

Aliases: C-type lectin domain family 13 member E antibody, C-type mannose receptor 2 antibody, CD 280 antibody, CD280 antibody, CD280 antigen antibody, CLEC 13E antibody, CLEC13E antibody, ENDO 180 antibody, ENDO180 antibody, Endocytic receptor (macrophage mannose receptor family) antibody, Endocytic receptor 180 antibody, FLJ35911 antibody, KIAA0709 antibody, Macrophage mannose receptor 2 antibody, Mannose receptor C type 2 antibody, MRC 2 antibody, MRC2 antibody, MRC2_HUMAN antibody, UPAR-associated protein antibody, UPARAP antibody, Urokinase plasminogen activator receptor associated protein antibody, Urokinase receptor associated protein antibody, Urokinase receptor-associated protein antibody, Urokinase-type plasminogen activator receptor-associated protein antibody

UniProt: Q9UBG0