E-cadherin antibody (AA 153-641)

Catalog No. ABIN7146190

This anti-E-cadherin antibody is a Rabbit Polyclonal antibody detecting E-cadherin in IHC, IF and ELISA. Suitable for Human.

Quick Overview for E-cadherin antibody (AA 153-641) (ABIN7146190)

Target: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This E-cadherin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-E-cadherin Antibody

Binding Specificity: AA 153-641

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cadherin-1 protein (153-641AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for E-cadherin

Target: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Alternative Name: CDH1

Background:

Background: Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

Aliases: Arc 1 antibody, CADH1_HUMAN antibody, Cadherin 1 antibody, cadherin 1 type 1 E-cadherin antibody, Cadherin-1 antibody, Cadherin1 antibody, CAM 120/80 antibody, CD 324 antibody, CD324 antibody, CD324 antigen antibody, cdh1 antibody, CDHE antibody, E-Cad/CTF3 antibody, E-cadherin antibody, ECAD antibody, Epithelial cadherin antibody, epithelial calcium dependant adhesion protein antibody, LCAM antibody, Liver cell adhesion molecule antibody, UVO antibody, Uvomorulin antibody

UniProt: P12830

Pathways: WNT Signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation