PRKACB antibody (Catalytic Subunit beta) (Biotin)
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- Target See all PRKACB Antibodies
- PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))
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Binding Specificity
- AA 2-53, Catalytic Subunit beta
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PRKACB antibody is conjugated to Biotin
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human cAMP-dependent protein kinase catalytic subunit beta protein (2-53AA)
- Isotype
- IgG
- Top Product
- Discover our top product PRKACB Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))
- Alternative Name
- PRKACB (PRKACB Products)
- Synonyms
- PKACB antibody, XPKAbeta antibody, kin-1 antibody, pkacb antibody, prkacba antibody, PRKACB antibody, prkacb antibody, wu:fz54b03 antibody, zgc:110804 antibody, Pkacb antibody, protein kinase cAMP-activated catalytic subunit beta antibody, protein kinase cAMP-activated catalytic subunit beta S homeolog antibody, protein kinase, cAMP-dependent, catalytic, beta antibody, protein kinase, cAMP-dependent, catalytic, beta b antibody, protein kinase, cAMP dependent, catalytic, beta antibody, PRKACB antibody, prkacb.S antibody, prkacb antibody, Prkacb antibody, prkacbb antibody
- Background
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Background: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.
Aliases: cAMP-dependent protein kinase catalytic beta subunit isoform 4ab antibody, cAMP-dependent protein kinase catalytic subunit beta antibody, KAPCB_HUMAN antibody, PKA C beta antibody, PKA C-beta antibody, PKACB antibody, Prkacb antibody, protein kinase A catalytic subunit beta antibody, Protein kinase cAMP dependent catalytic beta antibody
- UniProt
- P22694
- Pathways
- AMPK Signaling, Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism
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