CIRBP antibody (AA 1-172)

Catalog No. ABIN7361830

Product Details anti-CIRBP Antibody

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Binding Specificity: AA 1-172

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIRBP antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Cold-inducible RNA-binding protein (1-172AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CIRBP

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Alternative Name: CIRBP (CIRBP Products)

Synonyms: CIRP antibody, Cirp antibody, R74941 antibody, Xcirp antibody, cirbp antibody, cirbp-a antibody, cirbp2 antibody, cirp antibody, cirp1 antibody, cirp2 antibody, xcirp2 antibody, XCIRP antibody, XCIRP-1 antibody, cirbp-b antibody, cirp-1 antibody, APBP-1 antibody, zgc:136559 antibody, CIRBP antibody, A18 hnRNP antibody, cold inducible RNA binding protein antibody, cold-inducible RNA-binding protein antibody, cold inducible RNA binding protein S homeolog antibody, cold inducible RNA binding protein L homeolog antibody, cold inducible RNA binding protein b antibody, CIRBP antibody, EDI_107320 antibody, Cirbp antibody, cirbp.S antibody, cirbp.L antibody, cirbp antibody, cirbpb antibody

Background:

Background: Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3\\\'-untranslated regions (3\\\'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

Aliases: A18 hnRNP antibody, A18HNRNP antibody, cirbp antibody, CIRBP_HUMAN antibody, CIRP antibody, Cold inducible RNA binding protein antibody, Cold-inducible RNA-binding protein antibody, Glycine rich RNA binding protein antibody, Glycine-rich RNA-binding protein CIRP antibody, testicular tissue protein Li 39 antibody

UniProt: Q14011

Pathways: Ribonucleoprotein Complex Subunit Organization