DNAJA1 antibody (AA 8-106) (Biotin)

Catalog No. ABIN7150493

Product Details anti-DNAJA1 Antibody (Biotin)

Target: DNAJA1 (DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1))

Binding Specificity: AA 8-106

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJA1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DnaJ homolog subfamily A member 1 protein (8-106AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DNAJA1

Target: DNAJA1 (DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1))

Alternative Name: DNAJA1 (DNAJA1 Products)

Synonyms: DNAJA1 antibody, dj-2 antibody, dja1 antibody, hdj-2 antibody, hdj2 antibody, hsdj antibody, hsj2 antibody, hspf4 antibody, nedd7 antibody, Hsj2 antibody, Nedd7 antibody, DJ-2 antibody, DjA1 antibody, HDJ2 antibody, HSDJ antibody, HSJ2 antibody, HSPF4 antibody, NEDD7 antibody, hDJ-2 antibody, dnaja1l antibody, dnj-12 antibody, wu:fc14c09 antibody, zgc:55650 antibody, dnaJ homolog subfamily A member 1 pseudogene antibody, DnaJ heat shock protein family (Hsp40) member A1 antibody, DnaJ heat shock protein family (Hsp40) member A1 L homeolog antibody, DnaJ (Hsp40) homolog, subfamily A, member 1 antibody, LOC703360 antibody, dnaja1 antibody, DNAJA1 antibody, dnaja1.L antibody, Dnaja1 antibody

Background:

Background: Co-chaperone for HSPA8/Hsc70 (PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202).

Aliases: DJ 2 antibody, DJ2 antibody, DjA1 antibody, DnaJ (Hsp40) homolog, subfamily A, member 1 antibody, DnaJ homolog subfamily A member 1 antibody, DnaJ protein homolog 2 antibody, DNAJ2 antibody, Dnaja1 antibody, DNJA1_HUMAN antibody, hDJ 2 antibody, HDJ-2 antibody, HDJ2 antibody, Heat shock 40 kDa protein 4 antibody, heat shock protein DNAJ like 2 antibody, Heat shock protein J2 antibody, HSDJ antibody, HSJ-2 antibody, HSJ2 antibody, HSPF4 antibody, Human DnaJ protein 2 antibody, NEDD7 antibody, Neural precursor cell expressed developmentally down regulated 7 antibody, OTTHUMP00000021193 antibody

UniProt: P31689

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway