SHPRH antibody (AA 1362-1512) (Biotin)

Catalog No. ABIN7151214

Product Details anti-SHPRH Antibody (Biotin)

Target: SHPRH (SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH))

Binding Specificity: AA 1362-1512

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHPRH antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase SHPRH protein (1362-1512AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SHPRH

Target: SHPRH (SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase (SHPRH))

Alternative Name: SHPRH (SHPRH Products)

Synonyms: bA545I5.2 antibody, 2610103K11Rik antibody, AA450458 antibody, AU024614 antibody, BC006883 antibody, D230017O13Rik antibody, E130018M05 antibody, SNF2 histone linker PHD RING helicase antibody, SHPRH antibody, Shprh antibody

Background:

Background: E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to \'Lys-164\' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through \'Lys-63\'.

Aliases: bA545I5.2 antibody, E3 ubiquitin-protein ligase SHPRH antibody, FLJ27258 antibody, FLJ37625 antibody, FLJ45012 antibody, FLJ90837 antibody, histone-linker antibody, KIAA2023 antibody, MGC134886 antibody, PHD and RING finger domain-containing helicase antibody, Shprh antibody, SHPRH_HUMAN antibody, SNF2 antibody, SNF2 histone linker PHD RING helicase antibody

UniProt: Q149N8