F-Actin-Uncapping Protein LRRC16A (CARMIL1) (AA 1184-1295) antibody (HRP)

Catalog No. ABIN7378647

Product Details

Target: F-Actin-Uncapping Protein LRRC16A (CARMIL1)

Binding Specificity: AA 1184-1295

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human F-actin-uncapping protein LRRC16A protein (1184-1295AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: F-Actin-Uncapping Protein LRRC16A (CARMIL1)

Alternative Name: CARMIL1

Background:

Background: Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667).

Aliases: Acan 125 antibody, Capping protein, Arp2/3, and myosin I linker antibody, CARMIL homolog antibody, leucine rich repeat containing 16 antibody, Leucine-rich repeat-containing protein 16A antibody, LR16A_HUMAN antibody, Lrrc16 protein antibody, LRRC16A antibody, p116 antibody

UniProt: Q5VZK9