F-Actin-Uncapping Protein LRRC16A (CARMIL1) (AA 1321-1371) antibody

Catalog No. ABIN7450068

Product Details

Target: F-Actin-Uncapping Protein LRRC16A (CARMIL1)

Binding Specificity: AA 1321-1371

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunoprecipitation (IP), Western Blotting (WB)

Purpose: Rabbit anti-CARMIL Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: Between AA 1321 and 1371

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: F-Actin-Uncapping Protein LRRC16A (CARMIL1)

Alternative Name: CARMIL

Background: Background: CARMIL binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. It increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. CARMIL Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).CARMIL may control actin dynamics in lamellipodi and be required for cell migration [taken from the Universal Protein Resource (UniProt) Q5VZK9].

Gene ID: 55604

NCBI Accession: NP_060110

UniProt: Q5VZK9