KCNJ5 antibody (AA 348-419) (HRP)

Catalog No. ABIN7153292

Product Details anti-KCNJ5 Antibody (HRP)

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Binding Specificity: AA 348-419

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ5 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human G protein-activated inward rectifier potassium channel 4 protein (348-419AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KCNJ5

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Alternative Name: KCNJ5 (KCNJ5 Products)

Synonyms: CIR antibody, GIRK4 antibody, KATP1 antibody, KIR3.4 antibody, LQT13 antibody, Kir3.4 antibody, GIRK-4 antibody, KATP-1 antibody, potassium voltage-gated channel subfamily J member 5 antibody, potassium inwardly-rectifying channel, subfamily J, member 5 antibody, KCNJ5 antibody, Kcnj5 antibody

Background:

Background: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.

Aliases: Cardiac ATP sensitive potassium channel antibody, Cardiac inward rectifier antibody, CIR antibody, G protein activated inward rectifier potassium channel 4 antibody, G protein-activated inward rectifier potassium channel 4 antibody, GIRK 4 antibody, GIRK-4 antibody, GIRK4 antibody, Heart KATP channel antibody, Inward rectifier K(+) channel Kir3.4 antibody, Inward rectifier K+ channel KIR3.4 antibody, Inward rectifier potassium channel KIR3.4 antibody, inwardly rectifying subfamily J member 5 antibody, IRK-4 antibody, IRK5_HUMAN antibody, KATP 1 antibody, KATP-1 antibody, KATP1 antibody, KCNJ 5 antibody, Kcnj5 antibody, KIR 3.4 antibody, KIR3.4 antibody, LQT13 antibody, Potassium channel antibody, Potassium channel inwardly rectifying subfamily J member 5 antibody, Potassium inwardly rectifying channel J5 antibody, Potassium inwardly rectifying channel subfamily J member 5 antibody, potassium voltage-gated channel subfamily J member 5 antibody

UniProt: P48544

Pathways: Notch Signaling