GTF2H2 antibody (AA 1-157) (Biotin)

Catalog No. ABIN7153802

Product Details anti-GTF2H2 Antibody (Biotin)

Target: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Binding Specificity: AA 1-157

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2H2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human General transcription factor IIH subunit 2 protein (1-157AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GTF2H2

Target: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Alternative Name: GTF2H2 (GTF2H2 Products)

Synonyms: 44kDa antibody, BTF2 p44 antibody, BTF2-p44 antibody, Btf2p44 antibody, p44 antibody, BTF2 antibody, BTF2P44 antibody, T-BTF2P44 antibody, TFIIH antibody, general transcription factor II H, polypeptide 2 antibody, general transcription factor IIH subunit 2 antibody, general transcription factor IIH, polypeptide 2, 44kDa antibody, Gtf2h2 antibody, GTF2H2 antibody

Background:

Background: Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.

Aliases: Basic transcription factor 2 44 kDa subunit antibody, BTF2 antibody, BTF2 p44 antibody, BTF2-p44 antibody, BTF2P44 antibody, General transcription factor IIH antibody, General transcription factor IIH polypeptide 2 antibody, General transcription factor IIH subunit 2 antibody, General transcription factor IIH, polypeptide 2, 44 kDa antibody, Gtf2h2 antibody, MGC102806 antibody, p44 antibody, T BTF2P44 antibody, T-BTF2P44 antibody, TF2H2_HUMAN antibody, TFIIH antibody, TFIIH basal transcription factor complex p44 subunit antibody

UniProt: Q13888

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling