FOXA3 antibody (AA 220-336)

Catalog No. ABIN7155055

This anti-FOXA3 antibody is a Rabbit Polyclonal antibody detecting FOXA3 in ELISA and IHC. Suitable for Human.

Quick Overview for FOXA3 antibody (AA 220-336) (ABIN7155055)

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXA3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-FOXA3 Antibody

Binding Specificity: AA 220-336

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Hepatocyte nuclear factor 3-gamma protein (220-336AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FOXA3

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Alternative Name: FOXA3

Background:

Background: Transcription factor that is thought to act as a \\\'pioneer\\\' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis, binds to and activates transcription from the G6PC promoter. Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA. Binds to the CYP3A7 promoter together with members of the CTF/NF-I family. Involved in regulation of neuronal-specific transcription. May be involved in regulation of spermatogenesis.

Aliases: FKHH3 antibody, Fork head-related protein FKH H3 antibody, forkhead box A3 antibody, Forkhead box protein A3 antibody, Foxa3 antibody, FOXA3_HUMAN antibody, hepatic nuclear factor-3-beta antibody, hepatocyte nuclear factor 3 antibody, hepatocyte nuclear factor 3 gamma antibody, Hepatocyte nuclear factor 3-gamma antibody, HNF-3-gamma antibody, HNF-3G antibody, HNF3B antibody, HNF3G antibody, TCF-3G antibody, TCF3G antibody, Transcription factor 3G antibody

UniProt: P55318

Pathways: Carbohydrate Homeostasis