MED15 antibody (AA 433-530)

Catalog No. ABIN7159108

This anti-MED15 antibody is a Rabbit Polyclonal antibody detecting MED15 in WB, ELISA and IF. Suitable for Human.

Quick Overview for MED15 antibody (AA 433-530) (ABIN7159108)

Target: MED15 (Mediator Complex Subunit 15 (MED15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-MED15 Antibody

Binding Specificity: AA 433-530

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mediator of RNA polymerase II transcription subunit 15 protein (433-530AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MED15

Target: MED15 (Mediator Complex Subunit 15 (MED15))

Alternative Name: MED15

Background:

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway.

Aliases: MED15 antibody, ARC105 antibody, CTG7A antibody, PCQAP antibody, TIG1 antibody, TNRC7 antibody, Mediator of RNA polymerase II transcription subunit 15 antibody, Activator-recruited cofactor 105 kDa component antibody, ARC105 antibody, CTG repeat protein 7a antibody, Mediator complex subunit 15 antibody, Positive cofactor 2 glutamine/Q-rich-associated protein antibody, PC2 glutamine/Q-rich-associated protein antibody, TPA-inducible gene 1 protein antibody, TIG-1 antibody, Trinucleotide repeat-containing gene 7 protein antibody

UniProt: Q96RN5

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha