PAG1 antibody (AA 97-432) (Biotin)

Catalog No. ABIN7163392

The Biotin-conjugated Rabbit Polyclonal anti-PAG1 antibody (ABIN7163392) specifically detects PAG1 in ELISA. The antibody is reactive with Human samples.

Quick Overview for PAG1 antibody (AA 97-432) (Biotin) (ABIN7163392)

Target: PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAG1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-PAG1 Antibody (Biotin)

Binding Specificity: AA 97-432

Purpose: PAG1 Antibody, Biotin conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 protein (97-432AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PAG1

Target: PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))

Alternative Name: PAG1

Background:

Background: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

Aliases: CBP antibody, Csk binding protein antibody, Csk-binding protein antibody, FLJ37858 antibody, MGC138364 antibody, PAG 1 antibody, PAG antibody, PAG1 antibody, PAG1_HUMAN antibody, Phosphoprotein associated with glycosphingolipid enriched microdomains 1 antibody, Phosphoprotein associated with glycosphingolipid enriched microdomains antibody, Phosphoprotein associated with glycosphingolipid microdomains 1 antibody, Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 antibody, Protein Associated with Glycosphingolipid Enriched Microdomains antibody, Transmembrane adapter protein PAG antibody, Transmembrane phosphoprotein Cbp antibody

UniProt: Q9NWQ8

Pathways: p53 Signaling, TCR Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events