DTX2 antibody (AA 1-280)
Quick Overview for DTX2 antibody (AA 1-280) (ABIN7164418)
Target
See all DTX2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-280
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Probable E3 ubiquitin-protein ligase DTX2 protein (1-280AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DTX2 (Deltex Homolog 2 (DTX2))
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Alternative Name
- DTX2
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Background
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Background: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Aliases: Deltex 2 antibody, deltex homolog 2 (Drosophila) antibody, deltex, Drosophila, homolog of, 2 antibody, Deltex2 antibody, DTX2 antibody, DTX2_HUMAN antibody, hDTX2 antibody, Highly similar to hPMSR6 [H.sapiens] antibody, KIAA1528 antibody, Probable E3 ubiquitin-protein ligase DTX2 antibody, Protein deltex 2 antibody, Protein deltex-2 antibody, RING finger protein 58 antibody, RNF58 antibody, Zinc ion binding protein antibody
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UniProt
- Q86UW9
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Pathways
- Notch Signaling
Target
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