PTGES3 antibody (AA 1-110)

Catalog No. ABIN7164853

Product Details anti-PTGES3 Antibody

Target: PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))

Binding Specificity: AA 1-110

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGES3 antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Prostaglandin E synthase 3 protein (1-110AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PTGES3

Target: PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))

Alternative Name: PTGES3 (PTGES3 Products)

Synonyms: P23 antibody, TEBP antibody, cPGES antibody, PTGES3 antibody, 5730442A20Rik antibody, Ptges antibody, Tebp antibody, p23 antibody, sid3177 antibody, RGD1561913 antibody, CPGES antibody, cPGES-1 antibody, ptges3 antibody, wu:fb98d06 antibody, zgc:65804 antibody, zgc:77131 antibody, tebp antibody, wu:fb50a04 antibody, zgc:86751 antibody, prostaglandin E synthase 3 antibody, prostaglandin E synthase 3 (cytosolic) pseudogene antibody, prostaglandin E synthase 3a (cytosolic) antibody, prostaglandin E synthase 3 L homeolog antibody, prostaglandin E synthase 3b (cytosolic) antibody, PTGES3 antibody, LOC743066 antibody, Ptges3 antibody, ptges3a antibody, ptges3.L antibody, ptges3b antibody

Background:

Background: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway

Aliases: Co chaperone p23 antibody, cPGES antibody, Cytosolic prostaglandin E synthase antibody, Cytosolic prostaglandin E2 synthase antibody, Hsp90 co chaperone antibody, Hsp90 co-chaperone antibody, P23 antibody, Progesterone receptor complex antibody, Progesterone receptor complex p23 antibody, Prostaglandin E synthase 3 (cytosolic) antibody, Prostaglandin E synthase 3 antibody, PTGES 3 antibody, PTGES3 antibody, Sid 3177 antibody, TEBP antibody, TEBP_HUMAN antibody, Telomerase binding protein p23 antibody, Telomerase-binding protein p23 antibody, Unactive progesterone receptor 23 kD antibody

UniProt: Q15185

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Cellular Glucan Metabolic Process