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QTRT1 antibody (Catalytic Subunit 1) (Biotin)

QTRT1 Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7166919
  • Target See all QTRT1 Antibodies
    QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))
    Binding Specificity
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 211-403, Catalytic Subunit 1
    Reactivity
    • 35
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 33
    • 2
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This QTRT1 antibody is conjugated to Biotin
    Application
    • 26
    • 17
    • 3
    • 2
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)
    Isotype
    IgG
    Top Product
    Discover our top product QTRT1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))
    Alternative Name
    QTRT1 (QTRT1 Products)
    Synonyms
    CG4947 antibody, Dmel\\CG4947 antibody, TGT antibody, tgt antibody, zgc:66378 antibody, FP3235 antibody, TGUT antibody, 2610028E17Rik antibody, Tgt antibody, Tgut antibody, tRNA-guanine transglycosylase antibody, queuine tRNA-ribosyltransferase 1 S homeolog antibody, queuine tRNA-ribosyltransferase 1 antibody, queuine tRNA-ribosyltransferase catalytic subunit 1 antibody, Tgt antibody, Olsu_0732 antibody, Palpr_1298 antibody, Riean_1227 antibody, Calni_1240 antibody, Ftrac_0312 antibody, Ocepr_1541 antibody, Sulku_0977 antibody, Tmar_0854 antibody, Bache_2323 antibody, Nitsa_1291 antibody, Isop_1657 antibody, Despr_0021 antibody, Pedsa_1842 antibody, Corgl_1148 antibody, Mahau_0921 antibody, Theth_0831 antibody, qtrt1.S antibody, qtrt1 antibody, QTRT1 antibody, Qtrt1 antibody
    Background

    Background: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023, PubMed:20354154). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1\' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1\' of the ribose to form the product (By similarity).

    Aliases: FP3235 antibody, Guanine insertion enzyme antibody, qtrt1 antibody, Queuine tRNA ribosyltransferase 1 antibody, Queuine tRNA ribosyltransferase antibody, Queuine tRNA-ribosyltransferase antibody, TGT antibody, TGT, 43 KD subunit antibody, TGT, catalytic subunit antibody, TGT_HUMAN antibody, TGUT antibody, tRNA guanine transglycosylase antibody, tRNA-guanine transglycosylase antibody

    UniProt
    Q9BXR0
    Pathways
    Ribonucleoside Biosynthetic Process
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