RGS1 antibody (AA 1-181)

Catalog No. ABIN7167590

Product Details anti-RGS1 Antibody

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Binding Specificity: AA 1-181

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Regulator of G-protein signaling 10 protein (1-181AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RGS1

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Alternative Name: RGS1 (RGS1 Products)

Synonyms: 1R20 antibody, BL34 antibody, IER1 antibody, IR20 antibody, RGS1 antibody, 1r20 antibody, bl34 antibody, ier1 antibody, ir20 antibody, regulator of G protein signaling 1 antibody, regulator of G-protein signaling 1 antibody, regulator of G-protein signaling 1 S homeolog antibody, Regulator of G-protein signaling 1 antibody, RGS1 antibody, Rgs1 antibody, rgs1.S antibody, rgs1 antibody

Background:

Background: Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:8774883, PubMed:10608901, PubMed:9353196, PubMed:11443111, PubMed:18434541). Modulates the activity of potassium channels that are activated in response to CHRM2 signaling (PubMed:11443111). Activity on GNAZ is inhibited by palmitoylation of the G-protein (PubMed:9353196).

Aliases: Regulator of G protein signaling 10 antibody, Regulator of G-protein signaling 10 antibody, RGS10 antibody, RGS10_HUMAN antibody

UniProt: O43665

Pathways: MAPK Signaling, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events