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TGS1 antibody (AA 713-853) (HRP)

TGS1 Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7358031
  • Target See all TGS1 Antibodies
    TGS1 (Trimethylguanosine Synthase 1 (TGS1))
    Binding Specificity
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 713-853
    Reactivity
    • 17
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 15
    • 2
    Rabbit
    Clonality
    • 15
    • 2
    Polyclonal
    Conjugate
    • 13
    • 2
    • 1
    • 1
    This TGS1 antibody is conjugated to HRP
    Application
    • 12
    • 9
    • 7
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Trimethylguanosine synthase protein (713-853AA)
    Isotype
    IgG
    Top Product
    Discover our top product TGS1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TGS1 (Trimethylguanosine Synthase 1 (TGS1))
    Alternative Name
    TGS1 (TGS1 Products)
    Synonyms
    NCOA6IP antibody, PIMT antibody, PIPMT antibody, D4Ertd800e antibody, Ncoa6ip antibody, Pimt antibody, trimethylguanosine synthase 1 antibody, trimethylguanosine synthase 1 L homeolog antibody, TGS1 antibody, Tgs1 antibody, tgs1.L antibody
    Background

    Background: Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.

    Aliases: Cap specific guanine N2 methyltransferase antibody, Cap-specific guanine-N2 methyltransferase antibody, CLL associated antigen KW 2 antibody, CLL-associated antigen KW-2 antibody, DKFZp762A163 antibody, FLJ22995 antibody, HCA137 antibody, Hepatocellular carcinoma associated antigen 137 antibody, Hepatocellular carcinoma-associated antigen 137 antibody, NCOA6IP antibody, Nuclear receptor coactivator 6 interacting protein antibody, Nuclear receptor coactivator 6-interacting protein antibody, PIMT antibody, PIPMT antibody, PRIP interacting protein PIPMT antibody, PRIP interacting protein with methyltransferase domain antibody, PRIP interacting protein with methyltransferase motif antibody, PRIP-interacting protein with methyltransferase motif antibody, SEREX defined antibody, TGS 1 antibody, Tgs1 antibody, TGS1_HUMAN antibody, Trimethylguanosine synthase antibody, Trimethylguanosine synthase homolog (S. cerevisiae) antibody, Trimethylguanosine synthase homolog antibody

    UniProt
    Q96RS0
    Pathways
    Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization
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