VTCN1 antibody (AA 26-258)

Catalog No. ABIN7175204

Product Details anti-VTCN1 Antibody

Target: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Binding Specificity: AA 26-258

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VTCN1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human V-set domain-containing T-cell activation inhibitor 1 protein (26-258AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for VTCN1

Target: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Alternative Name: VTCN1 (VTCN1 Products)

Synonyms: B7h4 antibody, B7s1 antibody, B7x antibody, BC032925 antibody, B7-H4 antibody, B7H4 antibody, B7S1 antibody, B7X antibody, B7h.5 antibody, PRO1291 antibody, VCTN1 antibody, RGD1311204 antibody, V set domain containing T cell activation inhibitor 1 L homeolog antibody, V-set domain containing T cell activation inhibitor 1 antibody, V-set domain containing T-cell activation inhibitor 1 antibody, V set domain containing T cell activation inhibitor 1 antibody, vtcn1.L antibody, VTCN1 antibody, vtcn1 antibody, Vtcn1 antibody

Background:

Background: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.

Aliases: B7 family member, H4 antibody, B7 H4 antibody, B7 homolog 4 antibody, B7 superfamily member 1 antibody, B7 superfamily, member 1 antibody, B7-H4 antibody, B7h.5 antibody, B7h4 antibody, B7S1 antibody, B7x antibody, BC032925 antibody, Immune costimulatory protein B7-H4 antibody, Immune costimulatory protein B7H4 antibody, MGC41287 antibody, PRO1291 antibody, Protein B7S1 antibody, RP11 229A19.4 antibody, T cell costimulatory molecule B7x antibody, T-cell costimulatory molecule B7x antibody, V set domain-containing T cell activation inhibitor 1 antibody, V-set domain-containing T-cell activation inhibitor 1 antibody, VCTN1 antibody, Vtcn1 antibody, VTCN1_HUMAN antibody

UniProt: Q7Z7D3