FcRn antibody (AA 24-297) (Biotin)

Catalog No. ABIN7176832

Product Details anti-FcRn Antibody (Biotin)

Target: FcRn (IgG receptor FcRn (FcRn))

Binding Specificity: AA 24-297

Reactivity: Cynomolgus

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FcRn antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Cynomolgus

Purification: >95%, Protein G purified

Immunogen: Recombinant Macaca fascicularis IgG receptor FcRn large subunit p51 protein (24-297AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FcRn

Target: FcRn (IgG receptor FcRn (FcRn))

Alternative Name: FCGRT (FcRn Products)

Synonyms: FCRN antibody, alpha-chain antibody, FcRn antibody, Fc fragment of IgG receptor and transporter antibody, Fc receptor, IgG, alpha chain transporter antibody, FCGRT antibody, Fcgrt antibody

Background:

Background: Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus.

Aliases: FCGRT antibody, FCRNIgG receptor FcRn large subunit p51 antibody, FcRn antibody, IgG Fc fragment receptor transporter alpha chain antibody, Neonatal Fc receptor antibody

UniProt: Q8SPV9

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process