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CTCFL antibody (AA 1-636) (HRP)

CTCFL Reactivity: Mouse ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7177930
  • Target See all CTCFL Antibodies
    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
    Binding Specificity
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-636
    Reactivity
    • 28
    • 10
    • 3
    Mouse
    Host
    • 30
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 16
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTCFL antibody is conjugated to HRP
    Application
    • 28
    • 13
    • 13
    • 11
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Mouse Transcriptional repressor CTCFL protein (1-636AA)
    Isotype
    IgG
    Top Product
    Discover our top product CTCFL Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
    Alternative Name
    Ctcfl (CTCFL Products)
    Synonyms
    BORIS antibody, CT27 antibody, CTCF-T antibody, HMGB1L1 antibody, dJ579F20.2 antibody, CTCFL antibody, Boris antibody, OTTMUSG00000016680 antibody, CCCTC-binding factor like antibody, CCCTC-binding factor (zinc finger protein)-like antibody, CTCFL antibody, Ctcfl antibody
    Background

    Background: Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 \\\'Arg-3\\\' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites. Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.

    Aliases: Ctcfl antibody, Boris antibody, Transcriptional repressor CTCFL antibody, Brother of the regulator of imprinted sites antibody, CCCTC-binding factor antibody, CTCF paralog antibody, CTCF-like protein antibody

    UniProt
    A2APF3
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