SAA1 antibody

Catalog No. ABIN7179313

Product Details anti-SAA1 Antibody

Target: SAA1 (Serum Amyloid A1 (SAA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SAA1 antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: Protein G purified

Immunogen: Recombinant Serum amyloid A-1 Protein

Clone: 1F2E1

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 15mmol/L Sodium azide
Constituents: 0.1Mol/L Nacl

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SAA1

Target: SAA1 (Serum Amyloid A1 (SAA1))

Alternative Name: SAA1 (SAA1 Products)

Synonyms: PIG4 antibody, SAA antibody, SAA2 antibody, TP53I4 antibody, zgc:103580 antibody, SAA1 antibody, Saa-1 antibody, Saa2 antibody, serum amyloid A1 antibody, serum amyloid A antibody, amyloid protein A antibody, serum amyloid A protein antibody, serum amyloid a protein antibody, serum amyloid A 1 antibody, serum amyloid protein A antibody, SAA1 antibody, saa antibody, LOC694827 antibody, Sden_2438 antibody, Mmc1_0571 antibody, Riean_0971 antibody, Saa1 antibody, LOC100009168 antibody, LOC101120204 antibody

Background:

Background: Serum amyloid A protein, also named SAA, Amyloid protein A, Amyloid fibril protein AA, SAA1, SAA2 and PIG4, is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 is produced mainly in the liver and circulates in low levels in the blood. SAA1 may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex. The SAA1 cleavage product a designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver, spleen, and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis, they disrupt tissue structure and compromise performance.

Aliases: SAA1, Serum amyloid A-1 protein, Amyloid fibril protein AA

UniProt: P0DJI8

Pathways: Toll-Like Receptors Cascades