Ply (AA 2-471) antibody (HRP)

Catalog No. ABIN7352768

Product Details

Target: Ply

Binding Specificity: AA 2-471

Reactivity: Streptococcus pneumoniae

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA

Cross-Reactivity: Streptococcus pneumoniae

Purification: >95%, Protein G purified

Immunogen: Recombinant Streptococcus pneumoniae serotype 4 Pneumolysin protein (2-471AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Ply

Background:

Background: Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity).

Aliases: ply antibody, SP_1923 antibody, Pneumolysin antibody, Ply antibody, Thiol-activated cytolysin antibody

UniProt: P0C2J9