Cas3 (AA 120-226) antibody (HRP)

Catalog No. ABIN7179574

Product Details

Target: Cas3

Binding Specificity: AA 120-226

Reactivity: Thermus thermophilus

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA

Cross-Reactivity: Thermus thermophilus

Purification: >95%, Protein G purified

Immunogen: Recombinant Thermus thermophilus CRISPR-associated endonuclease/helicase Cas3 protein (120-226AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Cas3

Background:

Background: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity. The N-terminal domain (residues 6-260) acts as a ssDNA endonuclease, has no activity on dsDNA.

Aliases: cas3 antibody, TTHB187CRISPR-associated endonuclease/helicase Cas3 antibody, EC 3.1.-.- antibody, EC 3.6.4.- antibody, CRISPR-associated ssDNA endonuclease/helicase Cas3 antibody

UniProt: Q53VY2