HSP9AB1 (Ser254) antibody

Catalog No. ABIN7180024

Product Details

Target: HSP9AB1

Binding Specificity: Ser254

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human HSP90B around the phosphorylation site of serine 254 (V-G-S(p)-D-E).

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: HSP9AB1

Background:

Background: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Lothar Goretzki, AACR Meeting Abstracts, Apr 2006, 2006: 468.
Jean-Fran?ois Louvion, Mol. Biol. Cell, Nov 1998, 9: 3071.
Angelika Lueking, Mol. Cell. Proteomics, Dec 2003, 2: 1342.
Jason Fontana Circ, Res., May 2002, 90: 866.

Aliases: 90 kda heat shock protein beta HSP90 beta antibody, D6S182 antibody, FLJ26984 antibody, Heat shock 84 kDa antibody, Heat shock 90kD protein 1, beta antibody, Heat shock 90 kDa protein 1 beta antibody, Heat shock protein 90 alpha family class B member 1 antibody, Heat shock protein 90 kDa antibody, Heat shock protein 90 kDa alpha (cytosolic) class B member 1 antibody, Heat shock protein 90 kDa alpha family class B member 1 antibody, Heat shock protein beta antibody, Heat shock protein HSP 90 beta antibody, Heat shock protein HSP 90-beta antibody, HS90B_HUMAN antibody, HSP 84 antibody, HSP 90 antibody, HSP 90 b antibody, HSP 90b antibody, HSP84 antibody, HSP90 BETA antibody, hsp90ab1 antibody, HSP90B antibody, HSPC2 antibody, HSPCB antibody

UniProt: P08238