DYRK1B antibody

Catalog No. ABIN7183474

Product Details anti-DYRK1B Antibody

Target: DYRK1B (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYRK1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human DYR1B.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DYRK1B

Target: DYRK1B (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B))

Alternative Name: DYRK1B (DYRK1B Products)

Synonyms: DYRK1B antibody, MIRK antibody, Mirk antibody, DYRK1A antibody, dual specificity tyrosine phosphorylation regulated kinase 1B antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b antibody, DYRK1B antibody, Dyrk1b antibody

Background:

Background: Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments.

Lee K., Cancer Res. 60:3631-3637(2000).
Grimwood J., Nature 428:529-535(2004).
Lim S., . Biol. Chem. 277:25040-25046(2002).

Aliases: AOMS3 antibody, Dual specificity tyrosine (Y) phosphorylation regulated kinase 1B antibody, Dual specificity tyrosine phosphorylation regulated kinase 1B antibody, Dual specificity tyrosine-phosphorylation-regulated kinase 1B antibody, DYR 1B antibody, DYR1A antibody, DYR1B antibody, DYR1B_HUMAN antibody, DYRK 1B antibody, Dyrk1b antibody, Minibrain related kinase antibody, Minibrain-related kinase antibody, MIRK antibody, Mirk protein kinase antibody

UniProt: Q9Y463