SCN11A antibody (Internal Region)

Catalog No. ABIN7189376

Product Details anti-SCN11A Antibody

Target: SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCN11A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen Affinity Purified

Immunogen: Synthetic peptide corresponding to a region derived from internal residues of Human sodium channel, voltage-gated, type XI, alpha subunit

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in pH 7.3 PBS, 0.05 % Sodium azide, 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SCN11A

Target: SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))

Alternative Name: SCN11A (SCN11A Products)

Synonyms: SCN11A antibody, NSS2 antibody, NaN antibody, NaT antibody, SNS2 antibody, NAV1.9 antibody, SCN12A antibody, SNS-2 antibody, sodium voltage-gated channel alpha subunit 11 antibody, sodium channel protein type 11 subunit alpha antibody, sodium channel, voltage-gated, type XI, alpha antibody, SCN11A antibody, LOC100349709 antibody, Scn11a antibody

Background:

Background: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops, each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

Aliases: hNaN antibody, NaN antibody, NAV1.9 antibody, Peripheral nerve sodium channel 5 antibody, PN 5 antibody, PN5 antibody, SCN 11A antibody, SCN 12A antibody, Scn11a antibody, SCN12A antibody, SCNBA_HUMAN antibody, Sensory neuron sodium channel 2 antibody, SNS 2 antibody, SNS2 antibody, Sodium channel protein type 11 subunit alpha antibody, Sodium channel protein type XI subunit alpha antibody, Sodium channel voltage gated type XI alpha antibody, Sodium channel voltage gated type XI alpha polypeptide antibody, Sodium channel voltage gated type XI alpha subunit antibody, Sodium channel voltage gated type XII alpha polypeptide antibody, Voltage gated sodium channel Nav1.9 antibody, Voltage gated sodium channel subunit alpha Nav1.9 antibody, Voltage-gated sodium channel subunit alpha Nav1.9 antibody

UniProt: Q9UI33