CDH23 antibody (AA 30-110)

Catalog No. ABIN7224214

This Rabbit Polyclonal antibody specifically detects CDH23 in ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CDH23 antibody (AA 30-110) (ABIN7224214)

Target: CDH23 (Cadherin 23 (CDH23))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDH23 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-CDH23 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-Cadherin-23 Polyclonal Antibody

Specificity: Cadherin-23 Polyclonal Antibody detects endogenous levels of Cadherin-23 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Cadherin-23 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDH23

Target: CDH23 (Cadherin 23 (CDH23))

Alternative Name: Cadherin-23

Background: CDH23, KIAA1774, KIAA1812, Cadherin-23, OtocadherinCDH23 (cadherin related 23) is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. CDH23 is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of CDH23 may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.

Gene ID: 64072

UniProt: Q9H251

Pathways: Sensory Perception of Sound