KDM5B antibody

Catalog No. ABIN7191208

Product Details anti-KDM5B Antibody

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM5B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human KDM5B

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KDM5B

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Alternative Name: KDM5B (KDM5B Products)

Synonyms: jarid1b antibody, jarid1ba antibody, id:ibd5050 antibody, wu:fd15c05 antibody, cb264 antibody, jarid1bb antibody, plu1 antibody, wu:fc44h11 antibody, zgc:85741 antibody, JARID1B antibody, CT31 antibody, PLU-1 antibody, PLU1 antibody, PUT1 antibody, RBBP2H1A antibody, 2010009J12Rik antibody, 2210016I17Rik antibody, AW556288 antibody, D1Ertd202e antibody, Jarid1b antibody, Plu1 antibody, Rb-Bp2 antibody, mKIAA4034 antibody, RGD1565602 antibody, lysine (K)-specific demethylase 5Ba antibody, lysine (K)-specific demethylase 5Bb antibody, lysine demethylase 5B antibody, lysine (K)-specific demethylase 5B antibody, kdm5ba antibody, kdm5bb antibody, KDM5B antibody, Kdm5b antibody

Background:

Background: PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.

Aliases: Cancer/testis antigen 31 antibody, CT31 antibody, Histone demethylase JARID1B antibody, JARID1B antibody, Jumonji AT rich interactive domain 1B antibody, Jumonji/ARID domain-containing protein 1B antibody, Kdm5b antibody, KDM5B_HUMAN antibody, Lysine (K) specific demethylase 5B antibody, Lysine demethylase 5B antibody, Lysine specific demethylase 5B antibody, Lysine-specific demethylase 5B antibody, PLU-1 antibody, PLU1 antibody, PPP1R98 antibody, Protein phosphatase 1 regulatory subunit 98 antibody, PUT1 antibody, putative DNA/chromatin binding motif antibody, RBBP2H1A antibody, RBP2 like antibody, RBP2-H1 antibody, Retinoblastoma-binding protein 2 homolog 1 antibody, Retinoblastoma-binding protein 2 homolog 1A antibody

UniProt: Q9UGL1

Pathways: Warburg Effect