KISS1 antibody
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- Target See all KISS1 Antibodies
- KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KISS1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Cross-Reactivity
- Human, Mouse
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human KISS1
- Isotype
- IgG
- Top Product
- Discover our top product KISS1 Primary Antibody
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- Application Notes
- ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:5-1:20,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
- Alternative Name
- KISS1 (KISS1 Products)
- Synonyms
- HH13 antibody, KiSS-1 antibody, metastatin antibody, Eseptin antibody, KiSS-1 metastasis-suppressor antibody, KISS1 antibody, kiss1 antibody, Kiss1 antibody
- Background
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Background: This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.
Aliases: KISS 1 antibody, KiSS 1 metastasis suppressor antibody, Kiss1 antibody, KISS1_HUMAN antibody, Kisspeptin 1 antibody, Kisspeptin 10 antibody, Kisspeptin 13 antibody, Kisspeptin 14 antibody, Kisspeptin antibody, Kisspeptin-1 antibody, Kisspeptin-10 antibody, Kisspeptin-54 antibody, Kisspeptin1 antibody, Malignant melanoma metastasis suppressor antibody, Metastasis suppressor KiSS 1 antibody, Metastasis suppressor KiSS1 antibody, Metastin antibody, MGC39258 antibody
- UniProt
- Q15726
- Pathways
- Positive Regulation of Peptide Hormone Secretion
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