LZTS1 antibody

Catalog No. ABIN7191331

Product Details anti-LZTS1 Antibody

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZTS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human LZTS1

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:10-1:50,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LZTS1

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Alternative Name: LZTS1 (LZTS1 Products)

Synonyms: F37 antibody, FEZ1 antibody, Psdzip70 antibody, LZTS1 antibody, f37 antibody, fez1 antibody, leucine zipper tumor suppressor 1 antibody, leucine zipper, putative tumor suppressor 1 antibody, LZTS1 antibody, Lzts1 antibody, lzts1 antibody

Background:

Background: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

Aliases: F37 antibody, F37/esophageal cancer related gene coding leucine zipper motif antibody, F37/esophageal cancer-related gene-coding leucine-zipper motif antibody, Fez1 antibody, Leucine zipper putative tumor suppressor 1 antibody, Lzts1 antibody, LZTS1_HUMAN antibody, Psdzip70 antibody

UniProt: Q9Y250

Pathways: Synaptic Membrane