SLC7A11 antibody

Catalog No. ABIN7192521

Product Details anti-SLC7A11 Antibody

Target: SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC7A11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human SLC7A11

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:20-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SLC7A11

Target: SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))

Alternative Name: SLC7A11 (SLC7A11 Products)

Synonyms: SLC7A11 antibody, DKFZp468E122 antibody, CCBR1 antibody, xCT antibody, 9930009M05Rik antibody, AI451155 antibody, sut antibody, solute carrier family 7 member 11 antibody, solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 antibody, SLC7A11 antibody, Slc7a11 antibody

Background:

Background: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

Aliases: Amino acid transport system xc xCT antibody antibody, Amino acid transport system xc- antibody, Calcium channel blocker resistance protein CCBR1 antibody, Calcium channel blocker resistance protein CCBR1 antibody antibody, CCBR1 antibody, Cysteine/glutamate transporter antibody antibody, Cystine/glutamate transporter antibody, OTTHUMP00000164578 antibody, SLC7A11 antibody, Solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 antibody, solute carrier family 7 antibody, Solute carrier family 7 member 11 antibody, Solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 antibody, SYSTEM Xc(-) TRANSPORTER-RELATED PROTEIN antibody, xCT antibody, XCT_HUMAN antibody

UniProt: Q9UPY5