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CDO1 antibody (AA 101-200) (Cy5)

CDO1 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Cy5
Catalog No. ABIN715065
  • Target See all CDO1 Antibodies
    CDO1 (Cysteine Dioxygenase, Type I (CDO1))
    Binding Specificity
    • 15
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    AA 101-200
    Reactivity
    • 38
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 36
    • 3
    Rabbit
    Clonality
    • 38
    • 1
    Polyclonal
    Conjugate
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDO1 antibody is conjugated to Cy5
    Application
    • 26
    • 12
    • 12
    • 10
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CDO1
    Isotype
    IgG
    Top Product
    Discover our top product CDO1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CDO1 (Cysteine Dioxygenase, Type I (CDO1))
    Alternative Name
    CDO1 (CDO1 Products)
    Synonyms
    1300002L19Rik antibody, Cdo antibody, D18Ucla3 antibody, cysteine dioxygenase, type I antibody, cysteine dioxygenase 1, cytosolic antibody, cysteine dioxygenase type 1 antibody, NAEGRDRAFT_80458 antibody, Cdo1 antibody, CDO1 antibody
    Background

    Synonyms: Cysteine Dioxygenase Type 1, CDO 1, CDO, CDO I, CDO1, CDO-1, CDOI, Cytosolic cysteine dioxygenase, CDO1_HUMAN.

    Background: CDO1 (cysteine dioxygenase, type I) is a 200 amino acid protein that belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis. Existing as a monomer and expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart, CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine. Via its catalytic activity, CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell. Human CDO1 shares 94 % amino acid identity with its rat counterpart, suggesting a conserved role between species. The gene encoding CDO1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.PathwayOrganosulfur biosynthesis, taurine biosynthesis, hypotaurine from L-cysteine: step 1/2.

    Gene ID
    1036
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