YBX1 antibody

Catalog No. ABIN7193081

Product Details anti-YBX1 Antibody

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YBX1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human YBX1

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for YBX1

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Alternative Name: YBX1 (YBX1 Products)

Synonyms: BP-8 antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, MDR-NF1 antibody, NSEP-1 antibody, NSEP1 antibody, YB-1 antibody, YB1 antibody, Byb1 antibody, Cbfa antibody, Dbpb antibody, Ef1a antibody, Msy1 antibody, Nsep1 antibody, Yb1 antibody, bp-8 antibody, csda2 antibody, csdb antibody, dbpb antibody, frgy1 antibody, mdr-nf1 antibody, nsep-1 antibody, nsep1 antibody, yb1 antibody, 1700102N10Rik antibody, C79409 antibody, EF1A antibody, MSY1 antibody, dbpB antibody, mYB-1a antibody, nuclease sensitive element binding protein 1 antibody, Y-box binding protein 1 antibody, Y box binding protein 1 antibody, Y-box binding protein 1 S homeolog antibody, nuclease-sensitive element-binding protein 1 antibody, Y box protein 1 antibody, nsep1 antibody, YBX1 antibody, Ybx1 antibody, ybx1.S antibody, LOC479011 antibody

Background:

Background: This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).

Aliases: BP 8 antibody, CBF-A antibody, CCAAT binding transcription factor I subunit A antibody, CCAAT-binding transcription factor I subunit A antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, DNA binding protein B antibody, DNA-binding protein B antibody, EFI-A antibody, Enhancer factor I subunit A antibody, MDR NF1 antibody, MGC104858 antibody, MGC110976 antibody, MGC117250 antibody, NSEP 1 antibody, NSEP1 antibody, Nuclease sensitive element binding protein 1 antibody, Nuclease-sensitive element-binding protein 1 antibody, p50 antibody, Q15905 antibody, Y-box binding protein 1 antibody, Y-box transcription factor antibody, Y-box-binding protein 1 antibody, YB 1 antibody, YB-1 antibody, YBOX1_HUMAN antibody, YBX 1 antibody, ybx1 antibody

UniProt: P67809

Pathways: Regulation of Muscle Cell Differentiation