Calcitonin Receptor antibody (AA 410-490)

Catalog No. ABIN7227578

The Rabbit Polyclonal anti-Calcitonin Receptor antibody (ABIN7227578) specifically detects Calcitonin Receptor in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Calcitonin Receptor antibody (AA 410-490) (ABIN7227578)

Target: Calcitonin Receptor (CALCR)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calcitonin Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Calcitonin Receptor Antibody

Binding Specificity: AA 410-490

Purpose: Rabbit Anti-CALCR Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CALCR protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CALCR protein at AA range: 410-490

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Calcitonin Receptor

Target: Calcitonin Receptor (CALCR)

Alternative Name: CALCR

Background: Calcitonin receptor, CT-RCALCR encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in CALCR have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.

Molecular Weight: 53kD

Gene ID: 799

UniProt: P30988

Pathways: cAMP Metabolic Process