EPH Receptor A7 antibody (pTyr791)

Catalog No. ABIN7220294

The Rabbit Polyclonal anti-EPH Receptor A7 antibody (ABIN7220294) specifically detects EPH Receptor A7 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for EPH Receptor A7 antibody (pTyr791) (ABIN7220294)

Target: EPH Receptor A7 (EPHA7)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EPH Receptor A7 Antibody

Binding Specificity: pTyr791

Purpose: Rabbit Anti-EphA7 (phospho Tyr791) Polyclonal Antibody

Specificity: Phospho-EphA7 (Y791) Polyclonal Antibody detects endogenous levels of EphA7 protein only when phosphorylated at Y791.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human EphA7 Phospho-Tyr791

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EPH Receptor A7

Target: EPH Receptor A7 (EPHA7)

Alternative Name: EphA7

Background: EPHA7, EHK3, HEK11, Ephrin type-A receptor 7, EPH homology kinase 3, EHK-3, EPH-like kinase 11, EK11, hEK11EPHA7 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants.

Molecular Weight: 112kD

Gene ID: 2045

UniProt: Q15375

Pathways: RTK Signaling