FOXO3 antibody

Catalog No. ABIN7228548

This anti-FOXO3 antibody is a Rabbit Polyclonal antibody detecting FOXO3 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for FOXO3 antibody (ABIN7228548)

Target: FOXO3 (Forkhead Box O3 (FOXO3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXO3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOXO3 Antibody

Purpose: FKHRL1 Polyclonal Antibody

Specificity: This antibody detects endogenous levels of FKHRL1.

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human FKHRL1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FOXO3

Target: FOXO3 (Forkhead Box O3 (FOXO3))

Alternative Name: FKHRL1

Background: Rabbit Anti-FKHRL1 Polyclonal Antibody,Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1,FOXO3 (Forkhead Box O3) is a Protein Coding gene. Diseases associated with FOXO3 include Rhabdomyosarcoma and Cervix Carcinoma. Among its related pathways are IL-2 Pathway and Longevity regulating pathway. FOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of FOXO3 with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.,FKHRL1

Molecular Weight: observerd band 65kDa

Gene ID: 2309

UniProt: O43524

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis