GABRB2 antibody (C-Term)

Catalog No. ABIN7220888

This Rabbit Polyclonal antibody specifically detects GABRB2 in ELISA and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GABRB2 antibody (C-Term) (ABIN7220888)

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRB2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GABRB2 Antibody

Binding Specificity: C-Term

Purpose: GABAA Rβ2 Polyclonal Antibody

Specificity: GABAA Rβ2 Polyclonal Antibody detects endogenous levels of GABAA Rβ2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human GABAA range: Rbeta2

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GABRB2

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Alternative Name: GABAA Rbeta2

Background: Rabbit Anti-GABAA Rβ2 Polyclonal Antibody,GABRB2, Gamma-aminobutyric acid receptor subunit beta-2, GABA(A) receptor subunit beta-2,The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. GABRB2 encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion.,Gamma-aminobutyric acid receptor subunit beta-2

Gene ID: 2561

UniProt: P47870

Pathways: Sensory Perception of Sound, Synaptic Membrane