DOK3 antibody (AA 45-145)

Catalog No. ABIN716141

Product Details anti-DOK3 Antibody

Target: DOK3 (Docking Protein 3 (DOK3))

Binding Specificity: AA 45-145

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DOK3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DOK3

Target: DOK3 (Docking Protein 3 (DOK3))

Alternative Name: Dok3 (DOK3 Products)

Synonyms: DOK3 antibody, DOKL antibody, AI450713 antibody, Dokl antibody, docking protein 3 antibody, DOK3 antibody, Dok3 antibody

Background:

Synonyms: Docking protein 3, DOK 3, DOK Like Protein, DOKL Pending, Downstream of tyrosine kinase 3, p62 DOK Like Protein, DOK3_HUMAN.

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl functionDOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function. There are 4 isoforms generated by alternative splicing.

Gene ID: 79930