Otub (AA 21-110) antibody

Catalog No. ABIN716171

Product Details

Target: Otub

Binding Specificity: AA 21-110

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OTUB

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details

Target: Otub

Background:

Synonyms: C14orf137, Deubiquitinating enzyme OTUB2, OTB2, OTU domain containing ubiquitin aldehyde binding protein 2, OTU domain, ubiquitin aldehyde binding 2, OTU domain-containing ubiquitin aldehyde-binding protein 2, OTU2, Otub2, OTUB2_HUMAN, Otubain 2, Otubain-2, Ubiquitin specic processing protease OTUB2, Ubiquitin specic protease otubain 2, Ubiquitin thioesterase OTUB2, Ubiquitin-specic-processing protease OTUB2.

Background: This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function, to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde), an active cysteine protease site is present in the OTU domain.

Gene ID: 78990