RASGRF1 antibody (pSer916)

Catalog No. ABIN7218826

The Rabbit Polyclonal anti-RASGRF1 antibody (ABIN7218826) specifically detects RASGRF1 in ELISA, IHC (p) and IF. The antibody is reactive with Mouse and Rat samples.

Quick Overview for RASGRF1 antibody (pSer916) (ABIN7218826)

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASGRF1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-RASGRF1 Antibody

Binding Specificity: pSer916

Purpose: Ras-GRF1 (phospho Ser916) Polyclonal Antibody

Specificity: Phospho-Ras-GRF1 (S916) Polyclonal Antibody detects endogenous levels of Ras-GRF1 protein only when phosphorylated at S916.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Ras-GRF1 Phospho-Ser916

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RASGRF1

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Alternative Name: Ras-GRF1

Background: Rabbit Anti-Ras-GRF1 (phospho Ser916) Polyclonal Antibody,RASGRF1, CDC25, GNRP, GRF1, Ras-specific guanine nucleotide-releasing factor 1, Ras-GRF1, Guanine nucleotide-releasing protein, GNRP, Ras-specific nucleotide exchange factor CDC25,]RASGRF1 (Ras Protein Specific Guanine Nucleotide Releasing Factor 1) is a Protein Coding gene. Diseases associated with RASGRF1 include bleeding disorder, platelet-type, 18 and refractive error. Among its related pathways are Signaling by GPCR and Immune System. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGDS. romotes the exchange of Ras-bound GDP by GTP.,Ras-specific guanine nucleotide-releasing factor 1

Pathways: RTK Signaling, Cell Division Cycle, M Phase