RASGRF1 antibody (pSer916)

Catalog No. ABIN7218826

The Rabbit Polyclonal anti-RASGRF1 antibody (ABIN7218826) specifically detects RASGRF1 in IHC, ELISA, WB and IF. The antibody is reactive with Mouse and Rat samples.

Quick Overview for RASGRF1 antibody (pSer916) (ABIN7218826)

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASGRF1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-RASGRF1 Antibody

Binding Specificity: pSer916

Purpose: Rabbit Anti-Ras-GRF1 (phospho Ser916) Polyclonal Antibody

Specificity: Phospho-Ras-GRF1 (S916) Polyclonal Antibody detects endogenous levels of Ras-GRF1 protein only when phosphorylated at S916.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Ras-GRF1 Phospho-Ser916

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RASGRF1

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Alternative Name: Ras-GRF1

Background: RASGRF1, CDC25, GNRP, GRF1, Ras-specific guanine nucleotide-releasing factor 1, Ras-GRF1, Guanine nucleotide-releasing protein, GNRP, Ras-specific nucleotide exchange factor CDC25]RASGRF1 (Ras Protein Specific Guanine Nucleotide Releasing Factor 1) is a Protein Coding gene. Diseases associated with RASGRF1 include bleeding disorder, platelet-type, 18 and refractive error. Among its related pathways are Signaling by GPCR and Immune System. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGDS. romotes the exchange of Ras-bound GDP by GTP.

Pathways: RTK Signaling, Cell Division Cycle, M Phase