SUMO4 antibody

Catalog No. ABIN7231594

This Rabbit Polyclonal antibody specifically detects SUMO4 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for SUMO4 antibody (ABIN7231594)

Target: SUMO4 (Small Ubiquitin Related Modifier 4 (SUMO4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SUMO4 Antibody

Purpose: Rabbit Anti-SUMO4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SUMO4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SUMO4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SUMO4

Target: SUMO4 (Small Ubiquitin Related Modifier 4 (SUMO4))

Alternative Name: SUMO4

Background: Small ubiquitin-related modifier 4, SUMO-4, Small ubiquitin-like protein 4SUMO4 is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. Small Ubiquitin-Like Modifier 4 described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.

Molecular Weight: 10kD

Gene ID: 387082

UniProt: Q6EEV6