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Nlgn4l antibody (C-Term)

NLGN4L Reactivity: Mouse IF/ICC, IHC, WB Host: Mouse Monoclonal S98-7 unconjugated
Catalog No. ABIN7233051
  • Target
    Nlgn4l (NLGN4L) (Neuroligin 4-Like (NLGN4L))
    Binding Specificity
    AA 782-945, C-Term
    Reactivity
    Mouse
    Host
    Mouse
    Clonality
    Monoclonal
    Application
    Immunofluorescence (fixed cells) (IF/ICC), Immunohistochemistry (IHC), Western Blotting (WB)
    Purpose
    Anti-Neuroligin-4 Mouse Monoclonal Antibody
    Specificity
    This antibody recognizes mouse Neuroligin-4. It does not cross-react with other Neuroligins.
    Cross-Reactivity
    Mouse, Rat
    Immunogen
    Fusion protein corresponding to aa 782-945 (intracellular C-terminus) of mouse Neuroligin-4.
    Clone
    S98-7
    Isotype
    IgG1
  • Application Notes
    Immunoblotting: use at 1-2 μg/mL. A band of ~125-130 kDa is detected.
    Immunofluorescence: use at 10 μg/mL.
    These are recommended concentrations.
    Enduser should determine optimal concentrations for their application.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    Dilute in PBS or medium that is identical to that used in the assay system.
    Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    This product is stable for at least one (1) year at -20°C.
  • Target
    Nlgn4l (NLGN4L) (Neuroligin 4-Like (NLGN4L))
    Alternative Name
    Nlgn4l
    Synonyms
    NL-4 antibody, NL4 antibody, Nlgn4 antibody, Nlgn4x antibody, neuroligin 4-like antibody, Nlgn4l antibody
    Background
    Neuroligin 4-like,Cell surface protein involved in cell-cell-interactions. Plays a role in the formation or maintenance of synaptic junctions via its interactions (via the extracellular domains) with neurexin family members. Plays a role in synaptic signal transmission. {PubMed:18434543, PubMed:21282647}.,Neuroligin-4 is a neuronal cell surface protein and a member of the type-B carboxylesterase- lipase protein family. Members of this family may act as splice site-specific ligands for beta- neurexins and may be involved in the formation and remodeling of central nervous system synapses. Neuroligin-4 interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants.,Cell membrane, Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane. Note=Detected at glycinergic postsynapses in retina. Detected on dendritic spines on cultured neurons.,Neuroligin-4, NL-4
    UniProt
    B0F2B4
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