ADMA antibody

Catalog No. ABIN7233188

Product Details anti-ADMA Antibody

Target: ADMA (Asymmetrical Dimethylarginine (ADMA))

Reactivity: Please inquire

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADMA antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Purpose: Anti-Asymmetric Dimethyl Arginine Mouse Monoclonal Antibody

Specificity: This antibody reacts with free and bound ADMA. It does not cross-react with free or bound arginine or NG- monomethyl arginine.

Immunogen: Dimethyl-L-arginine

Clone: 21C7

Isotype: IgM

Application Details

Application Notes: Immunoblotting: use at 1-2 μg/mL
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations.
End user should determine optimal concentrations for their applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute lyophilized antibody using ultrapure to a final concentration no less than 100 μg/mL. Reconstitution with PBS or Tris buffer is acceptable if required. Protein carrier, biocide or cryopreservative can be added as needed. Aliquot and store at -20C for longterm storage. Dilute immediately prior to use.

Buffer: 0.1M Tris, 0.1M glycine, 2 % sucrose

Storage: -20 °C,-80 °C

Storage Comment: This product is stable for at least one (1) year at -20°C to -70°C. Reconstituted product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles.

Target Details for ADMA

Target: ADMA (Asymmetrical Dimethylarginine (ADMA))

Alternative Name: Asymmetric Dimethyl Arginine (ADMA Products)

Target Type: Amino Acid

Background: Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by- product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical involved in normal endothelial function and, by extension, cardio- vascular health. Since raised levels of ADMA appear to be associated with adverse human health consequences for cardiovascular disease, metabolic diseases, and also a wide range of diseases of the elderly, the possible lowering of ADMA levels may have important therapeutic effects.