CACNA1H antibody (AA 260-360)

Catalog No. ABIN7266015

Product Details anti-CACNA1H Antibody

Target: CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))

Binding Specificity: AA 260-360

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1H antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: CACNA1H Rabbit pAb

Sequence: CFLDSAFVRN NNLTFLRPYY QTEEGEENPF ICSSRRDNGM QKCSHIPGRR ELRMPCTLGW EAYTQPQAEG VGAARNACIN WNQYYNVCRS GDSNPHNGAI N

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 260-360 of human CACNA1H (NP_066921.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CACNA1H

Target: CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))

Alternative Name: CACNA1H (CACNA1H Products)

Synonyms: CACNA1HB antibody, Cav3.2 antibody, ECA6 antibody, EIG6 antibody, MNCb-1209 antibody, alpha13.2 antibody, calcium voltage-gated channel subunit alpha1 H antibody, calcium channel, voltage-dependent, T type, alpha 1H subunit antibody, CACNA1H antibody, Cacna1h antibody

Background: This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE).,CACNA1H,CACNA1HB,Cav3.2,ECA6,EIG6,HALD4,Signal Transduction,Neuroscience,Calcium Signaling,CACNA1H

Molecular Weight: 258kDa/259kDa

Gene ID: 8912

UniProt: O95180

Pathways: C21-Steroid Hormone Metabolic Process