CPB2 antibody (AA 310-410)

Catalog No. ABIN7266081

Product Details anti-CPB2 Antibody

Target: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Binding Specificity: AA 310-410

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPB2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: CPB2 Rabbit pAb

Sequence: HSYSQHIVFP YSYTRSKSKD HEELSLVASE AVRAIEKISK NTRYTHGHGS ETLYLAPGGG DDWIYDLGIK YSFTIELRDT GTYGFLLPER YIKPTCREAF A

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 310-410 of human CPB2 (NP_001863.3).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CPB2

Target: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Alternative Name: CPB2 (CPB2 Products)

Synonyms: CPU antibody, PCPB antibody, TAFI antibody, 1110032P04Rik antibody, 4930405E17Rik antibody, AI255929 antibody, CPR antibody, Cpu antibody, pCPB antibody, zgc:112493 antibody, carboxypeptidase B2 antibody, carboxypeptidase B2 (plasma) antibody, CPB2 antibody, Cpb2 antibody, cpb2 antibody

Background: Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants.,CPB2,CPU,PCPB,TAFI,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Cardiovascular,Blood,Coagulation,Serum Proteins,Heart,Cardiovascular diseases,Heart disease,CPB2

Molecular Weight: 40kDa/48kDa

Gene ID: 1361

UniProt: Q96IY4

Pathways: Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis