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PD-L1 antibody

PD-L1 Reactivity: Human WB, FACS, ELISA, InhA Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7266180
  • Target See all PD-L1 Antibodies
    PD-L1 (CD274 (PD-L1))
    Reactivity
    • 167
    • 106
    • 63
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    Human
    Host
    • 126
    • 59
    • 15
    • 4
    • 4
    • 1
    Rabbit
    Clonality
    • 108
    • 99
    • 2
    Monoclonal
    Conjugate
    • 97
    • 14
    • 13
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    This PD-L1 antibody is un-conjugated
    Application
    • 137
    • 101
    • 59
    • 40
    • 37
    • 28
    • 17
    • 16
    • 16
    • 15
    • 10
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Inhibition Assay (InhA)
    Purpose
    PD-L1/CD274 Rabbit mAb
    Cross-Reactivity
    Human
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Purity
    ≥95 % purity by SDS-PAGE
    Immunogen
    Recombinant protein of human PD-L1/CD274.
    Isotype
    IgG
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • Application Notes
    Elisa,1:500 - 1:2000,WB,1:500 - 1:2000,FC,1:50 - 1:200,Inhibition,1 μg/ul
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.09 % sodium azide, 50 % glycerol, pH 7.4.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PD-L1 (CD274 (PD-L1))
    Alternative Name
    PD-L1 (PD-L1 Products)
    Synonyms
    B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
    Background
    Programmed death-ligand 1 (PD-L1) is a 40 kDa type 1 transmembrane protein that suppresses immune system. PD-L1 is expressed in hematopoietic and non-hematopoietic cells including T cells and B cells and various types of tumor cells. PD-L1 binds to its receptor Programmed death 1 (PD1). During infection or inflammation, PD1-PD-L1 interaction is important for preventing autoimmunity. In tumor microenvironments, PD1-PD-L1 interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human cancers. In recent years, PD-L1 has become an important biomarker and immunotherapy target for many types of malignancies.,B7-H,B7H1,PDL1,PD-L1,PDCD1L1,PDCD1LG1,CD274,Immunology & Inflammation,CD markers,PD-L1
    Molecular Weight
    20kDa/33kDa
    Gene ID
    29126
    UniProt
    Q9NZQ7
    Pathways
    Cancer Immune Checkpoints
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