CHP1 antibody, CHP-1 antibody, MGC89160 antibody, NV16801 antibody, Chp-1 antibody, Morgana antibody, 1110001O09Rik antibody, AA409036 antibody, morgana antibody, zgc:63894 antibody, cysteine and histidine rich domain containing 1 antibody, cysteine and histidine-rich domain-containing protein antibody, cysteine and histidine rich domain containing 1 S homeolog antibody, cysteine and histidine-rich domain (CHORD)-containing 1 antibody, cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 antibody, cysteine and histidine-rich domain (CHORD) containing 1b antibody, CHORDC1 antibody, Chordc1 antibody, LOC412067 antibody, chordc1.S antibody, chordc1 antibody, chordc1b antibody
Background
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling. Involved in stress response. Prevents tumorigenesis.,CHORDC1,CHP1,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,CHORDC1