CYP27A1 antibody (AA 200-400)

Catalog No. ABIN7266656

Product Details anti-CYP27A1 Antibody

Target: CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))

Binding Specificity: AA 200-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP27A1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: CYP27A1 Rabbit pAb

Sequence: NQVSDMAQLF YYFALEAICY ILFEKRIGCL QRSIPEDTVT FVRSIGLMFQ NSLYATFLPK WTRPVLPFWK RYLDGWNAIF SFGKKLIDEK LEDMEAQLQA AGPDGIQVSG YLHFLLASGQ LSPREAMGSL PELLMAGVDT TSNTLTWALY HLSKDPEIQE ALHEEVVGVV PAGQVPQHKD FAHMPLLKAV LKETLRLYPV V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human CYP27A1 (NP_000775.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CYP27A1

Target: CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))

Alternative Name: CYP27A1 (CYP27A1 Products)

Synonyms: CP27 antibody, CTX antibody, CYP27 antibody, Cyp27 antibody, P450C27 antibody, 1300013A03Rik antibody, cytochrome P450 family 27 subfamily A member 1 antibody, cytochrome P450, family 27, subfamily a, polypeptide 1 antibody, cytochrome P450, family 27, subfamily A, polypeptide 1 antibody, sterol 26-hydroxylase, mitochondrial antibody, CYP27A1 antibody, Cyp27a1 antibody, cyp27a1 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.,CYP27A1,CP27,CTX,CYP27,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Mitochondrial markers,Lipid Metabolism,Cholesterol Metabolism,Cytochromes,Lipases,Cardiovascular,Lipids,CYP27A1

Molecular Weight: 60kDa

Gene ID: 1593

UniProt: Q02318